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劳拉陆军预备役

劳拉陆军预备役

Interim Associate Provost, Professor of 化学istry

stultz-laura.jpg办公室:

芒格大厅211

Contact Information:

Birmingham-南部 College
549001箱
Division of Science and Mathematics
阿卡德尔菲路900号
Birmingham, AL 35254
Office Phone: (205) 226-4660
电子邮件: (电子邮件保护)

Brief Career Background:

Dr. Stultz obtained her Ph.D. in 化学istry from the University of North Carolina at Chapel Hill working with Professor Thomas Meyer. In her doctoral research she studied the mechanism of oxidation reactions involving ruthenium polypyridyl complexes. She conducted her postdoctoral research with Professor George Christou at Indiana University studying the reactions of rhodium and ruthenium dimers with biomolecules. She joined the faculty of Birmingham-南部 College in 1997 and has served Chair of the Department of 化学istry and 理论物理ics and as an Area Chair. She enjoys traveling with students during Eterm and working with undergraduate researchers.

Educational Background:

B.A. 化学istry, Oberlin College 1986
Ph.D. 化学istry, University of North Carolina at Chapel Hill 1995.

研究总结:

Dr. Stultz and her students investigate the chemistry of metal containing anti-cancer drugs. Recent work has focused on the ruthenium complexes KP1019 and KP1339. These complexes undergo ligand exchange and reduction reactions under biological conditions, which have been shown to affect their cytotoxicity. To understand the 动力学 and mechanisms of these reactions, the complexes are studied using 电化学, NMR and UV-vis 光谱学. Dr. Stultz also develops course-based undergraduate research experiences (CUREs) to provide opportunities for students to engage in authentic research in their classes.

课程:

CH 111 SM Atoms and 摩尔ecules
A first course in general chemistry that examines the structure of atoms and molecules.  主题包括 components of matter, 原子结构, 周期性规律, bonding and molecular structure, 化学反应, 化学计量学, 气体的行为, and thermochemistry.

CH 112 Reactions and Mechanisms
一个continuation of general chemistry that builds on the foundations established in CH 111.  主题包括 intermolecular forces, colligative properties, 热力学, 平衡, 电化学, 和动力学.

CH 149 ES, SM 化学ical Principles
A one-term general chemistry course for students with a strong background in chemistry. 主题包括 molecular structure, 光谱学, 化学计量学, 热力学, 动力学, oxidation-reduction reactions, 酸碱反应, 平衡, 和缓冲.  The topics taught in the context of real-world issues including climate change, computer chip development, and anti-cancer drugs.

CH 306 WR- Inorganic 化学istry
A course containing both theoretical and descriptive inorganic chemistry. 主题包括 coordination chemistry, group theory and symmetry, crystal field theory, molecular orbital theory, reaction mechanisms, organometallic chemistry and bioinorganic chemistry.

CH 410 Senior Research in 化学istry
A capstone research experience during the senior year. Requirements include a paper in the style of a scientific journal article and an oral presentation to students and faculty.

SN 299 Eterm in Ecuador
A three-week immersion in Spanish language and Ecuadorian culture, based in Cuenca, Ecuador.

CH 299 Introduction to Research
A one-month class project designed to give students hands-on experience with research early in their college career. In addition to conducting an independent research project, students will learn about the ethics of research, searching the chemical literature, experimental design, and scientific writing.

Publications From Research at 365英国上市官网 - *365英国上市官网 student researcher

DMSO reduces the cytotoxicity of anticancer ruthenium complex KP1019 in yeast. 戴维斯J.; *Cetto, A.; *Campbell, M; *Scoggins, S.; 陆军预备役,L.; 汉森,P. microPublication Biology, 2021 http://doi.org/10.17912 / micropub.生物学.000436.

Proteomic Analysis of S. 酵母 Response to the Anticancer Ruthenium Complex KP1019.  陆军预备役,L. K.; *Hunsucker, A.*米德尔顿,S.; *Grovenstein, E.; *O’Leary, J.; Blatt, E.; Miller, M.; Mobley, J.; 汉森,P. K. Metallomics 2020, 12, 876-890.

DNA Damage Response Checkpoint Activation Drives KP1019 Dependent Pre-Anaphase Cell Cycle Delay in S. 酵母.  Bierle L. A.; Reich, K. L.; Taylor, B. E.; Blatt, E. B.; *Middleton, S. M.; Burke, S. D.; 陆军预备役,L. K.; 汉森,P. K.; Partridge, J. F.; Miller, M. E. 公共科学图书馆 一个, 2015, 10(9) e0138085. 

Collaboration-Focused Workshop for Interdisciplinary, Inter-Institutional Teams of College Science 教师. 汉森,P. K.; 陆军预备役,L. Journal of Science College 教学  2015, 44, 6, 30. 

The Anticancer Ruthenium Complex KP1019 Induces DNA Damage, Leading to Cell Cycle Delay and Cell Death in Saccharomyces 酵母. 史蒂文斯,年代. K.; Strehle, A. P.; Miller, R. L.;*Gammons,年代. H,; *霍夫曼,K. J.; *McCarty, J. T.; Miller, M. E.; 陆军预备役,L. K.; 汉森,P. K. 摩尔 杂志. 2013,  83(1), 225. 

Third-order Nonlinearities of Tetrakis(2,2’-dipyridyl)diruthenium 复合物. 太阳,W; *巴顿,T. H.; 陆军预备役,L. K.; Claude, J. P. Optics 通信, 2003; 218, 189.

Medium Dependence of Intramolecular Vibrational Modes Coupled to MLCT Transitions in Metal Polypyridyl 复合物. Kestell J; *威廉姆斯,Z. L.; 陆军预备役,L. K.; Claude, J. P. J. 理论物理. 化学. A.; (Article); 2002; 106(24), 5768.